The present study was undertaken to investigate the effectiveness of the ethanolic extract of Echinophora platyloba DC. on Candida albicans. Using the agar dilution method, the growth condition of standard Candida albicans ATCC 10231, cultured on the media containing plant extracts at different concentrations (1, 2, 4, 8, 16, 32, 64, 128 and 256 mg/ml) was studied. The results were recorded twenty one days after the incubation period, maximum time for the growth of fungi. Results showed that the extract of Echinophora platyloba, equal or above the concentration of 2mg/ml, effectively inhibits the growth of Candida albicans. In other words it shows growth on media containing 1mg/ml of the extract. Results of the present study revealed a great promise in the application of Echinophora platyloba extract against Candida albicans. It is concluded that the plant studied could be a good antifungal source.