Results: From 105 subjects 68 people completed the study (33 persons in cedar group and 35 persons in placebo group). The mean and standard deviation of the age was 26.1 ± 7.5 years and 22 subjects (32.4%) were male. TLC and ASI in the sixth and eighth weeks in cedar group were significantly
less than in placebo group (p < 0.001). Topical cedar solution had no serious side effects.
Conclusion: The topical cedar solution plus clindamycin 1% was more effective and safe than placebo
plus 1% clindamycin for the treatment of acne vulgaris