Background: Mycosis fungoides (MF) is the most common and indolent form of cutaneous T-cell lymphomas (CTCL), that usually occurs in old adults. We aimed to determine epidemiologic features and patients’ characteristics of Mycosis fungoides in Isfahan, Iran Methods: We performed a retrospective study in Mycosis fungoides clinic of Alzahra hospital, that is the main center for treatment of patients with Mycosis fungoides in Isfahan, and evaluated clinicopathologic features of the disease Findings: In 3 years, from 25 referred patients, 18 were diagnosed as Mycosis fungoides. Seven (38.9%) patients were men and 11 (61.1%) were women with male to female ratio of 1:1.57. The mean age of patients was 41.06 years. 88.9% of patients were in stages ΙA and ΙB Conclusion: Most of our patients presented in early stages that were similar to other studies; while male to female ratio was different from other studies