Soft tissue augmentation by autologous cultured fibroblasts transplantation for treatment of wrinkles and scars: a case series of 20 patients

There are many filler agents for augmentation of static wrinkles and atrophic scars from synthetic, bio-synthetic, cadaver, animal and human sources METHODS The current study presents 20 patients whose facial wrinkles and lines were treated by transplantation of autologous cultured fibroblasts. The fibroblast nature of cells was confirmed by immune-staining and flow cytometry RESULTS The mean of improvement for this procedure at the 6 month follow up was 41% CONCLUSIONS In conclusion autologous fibroblast transplantation can be an effective procedure for correction of wrinkles and atrophic scars